Innovative Solutions for Automated Imaging

MetaSystems has been developing and producing system software for automated microscopy since 1986. Today, users in more than 100 countries rely on the laboratory solutions by MetaSystems.

In addition to generating the highest quality images, our modern approaches include an advanced workflow management that grows with your requirements and the use of artificial intelligence for image assessment.

To learn more about our innovative lab solutions, we encourage you to begin on the applications pages.

You would like to discover what others are accomplishing with their MetaSystems products? Read through the list of peer-reviewed publications from our customers!

If you do not find what you are looking for, please do not hesitate to contact the MetaSystems partner in your region.

Machine-assisted interpretation of auramine stains substantially increases through-put and sensitivity of microscopic tuberculosis diagnosis

Of all bacterial infectious diseases, infection by Mycobacterium tuberculosis poses one of the highest morbidity and mortality burdens on humans throughout the world. Due to its speed and cost-efficiency, manual microscopy of auramine-stained sputum smears remains a crucial first-line detection method. However, it puts considerable workload on laboratory staff and suffers from a limited sensitivity. Here we validate a scanning and analysis system that combines fully-automated microscopy with deep-learning based image analysis. After automated scanning, the system summarizes diagnosis-relevant image information and presents it to the microbiologist in order to assist diagnosis. We tested the benefit of the automated scanning and analysis system using 531 slides from routine workflow, of which 56 were from culture positive specimen. Assistance by the scanning and analysis system allowed for a higher sensitivity (40/56 positive slides detected) than manual microscopy (34/56 positive slides detected), while greatly reducing manual slide-analysis time from a recommended 5-15 min to around 10 s per slide on average.

Cited From: Tuberculosis (Edinburgh, Scotland) (2020) Read more...
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